M-110 [1395048-49-3]

TargetMol Chemicals

M-110 [1395048-49-3]

9

1395048-49-3

Chemical

Research Use Only

M-110

98.30%

C22H28ClN5O3

445.94

M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases, showing a preference for PIM-3 (IC50=47 nM), and inhibits PIM-1 and PIM-2 with similar IC50s of 2.5 microM. M-110 also inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 microM.

3 years

CC\C(=N/NC(=O)c1ccnc(NCCCN2CCOCC2)c1)c1ccc(Cl)cc1O

-20°C

12352200