M1002 [823830-85-9]

TargetMol Chemicals

M1002 [823830-85-9]

9

823830-85-9

Chemical

Research Use Only

M1002

99.73%

C15H8F6N2O2S

394.29

M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist that enhances the affinity of HIF-2alpha and ARNT for transcriptional activation. It alters the Tyr2 conformation of the HIF-2alpha PAS-B structural domain and acts synergistically with inhibitors of the prolyl hydroxylase structural domain (PHD).

3 years

FC(F)(F)C1=CC(=CC(NC2=NS(=O)(=O)C3=CC=CC=C23)=C1)C(F)(F)F

-20°C

12352200