M4 mAChR Modulator-1

TargetMol Chemicals

M4 mAChR Modulator-1

9

Research Use Only

M4 mAChR Modulator-1 (compound 23i) acts as a positive allosteric modulator (PAM) of the M4 mAChR. It demonstrates a stronger synergistic effect in beta-arrestin recruitment compared to G protein activation when interacting with ACh. Additionally, while its PAM effects are weaker in G protein-mediated responses, they are more potent in beta-arrestin recruitment.

-20°C

12352200