Velzatinib [2590556-80-0]

MedChem Express

Velzatinib [2590556-80-0]

10

2590556-80-0

Research Use Only

99.47

C29H32N8O

508.62

Velzatinib (M4205) is a multi-target inhibitor for PDGFRB, PDGFRA, CSF1R, c-Kit, FLT3, and LCK, with an IC50s of 2.6, 50, 5.5, 44, 141 and 141 nM, respectively. Velzatinib exhibits antitumor efficacy in xenograft mouse models[1].

CN1N=CC(C2=CC=C(CNC3=NC=NC(C4=CN=C5C=C(C=CN54)OCCCN6CCCC6)=C3)C=C2)=C1

-20°C,2°C to 8°C

12352200