m7(3Ma-Biotin)Gppp(2OMe)ApG ammonium

MedChem Express

m7(3Ma-Biotin)Gppp(2OMe)ApG ammonium

5

Research Use Only

25 mM

90.00

C43H60N18O25P4S.xNH3

1385.00 (free base)

m7(3Ma-Biotin)Gppp(2OMe)ApG ammonium is a Biotin-labled cap analogue that can be used for mRNA synthesis. The efficiency of mRNA delivery can be determined by the detection of Biotin by flow cytometry, which can be used to track mRNA in cells and in living animals and to screen delivery lipid ratios.

O=C1C([N+](C)=CN2[C@H]3[C@H](O)[C@H](CNC(CCCC[C@@H]4SC[C@]([C@]4([H])N5)([H])NC5=O)=O)[C@@H](COP(OP(OP(OC[C@H]6O[C@@H](N(C=N7)C8=C7C(N)=NC=N8)[C@H](OC)[C@@H]6OP(OC[C@H]9O[C@@H](N(C=N%10)C%11=C%10C(NC(N)=N%11)=O)[C@H](O)[C@@H]9O)([O-])=O)(O)=O)(O)=O)(O)=O)O3)=C2N=C(N)N1.N.[x]

-20°C

41115811