ProductsBack/MAC glucuronide alpha-hydroxy lactone-linked SN-38 [2246380-70-9]

MAC glucuronide alpha-hydroxy lactone-linked SN-38 [2246380-70-9]

Name: MAC glucuronide alpha-hydroxy lactone-linked SN-38 [2246380-70-9]
SKU: HY-128942_M09
Availability: BackOrder

HY-128942

Product group Molecular Biology

Overview

Supplier
MedChem Express
Product Name
MAC glucuronide alpha-hydroxy lactone-linked SN-38 [2246380-70-9]
Delivery Days Customer
10
CAS Number
2246380-70-9
Certification
Research Use Only
Estimated Purity
95.89
Molecular Formula
C50H54N6O20S
Molecular Weight
1091.06
Scientific Description
MAC glucuronide alpha-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a stabilized lactone MAC glucuronide alpha-hydroxy lactone-linked SN-38 agent linker. MAC glucuronide alpha-hydroxy lactone-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 99 and 105 ng/mL, respectively[1].
SMILES
O=C([C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC2=CC=C(COC(N(CO[C@](C3=C(CO4)C(N5CC6=C(CC)C7=CC(O)=CC=C7N=C6C5=C3)=O)(CC)C4=O)CCS(=O)(C)=O)=O)C=C2NC(CN(C)C(CCN8C(C=CC8=O)=O)=O)=O)O1)O
Storage Instruction
-20°C,2°C to 8°C
UNSPSC
41115800