MAC glucuronide phenol-linked SN-38 [2246380-69-6]
T18538
CAS Number2246380-69-6
Product group Chemicals
Molecular Weight1091.06
Overview
- SupplierTargetMol Chemicals
- Product NameMAC glucuronide phenol-linked SN-38
- Delivery Days Customer9
- CAS Number2246380-69-6
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameMAC glucuronide phenol-linked SN-38
- Molecular FormulaC50H54N6O20S
- Molecular Weight1091.06
- Scientific DescriptionMAC glucuronide phenol-linked SN-38, a pH-sensitive lactone and DNA topoisomerase I inhibitor drug linker, exhibits cytotoxicity in L540cy and Ramos cells, with IC50 values of 113 ng/mL and 67 ng/mL, respectively[1].
- Shelf life instruction3 years
- SMILESCCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2ccc(OCN(CCS(C)(=O)=O)C(=O)OCc3ccc(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)c(NC(=O)CN(C)C(=O)CCN4C(=O)C=CC4=O)c3)cc12
- Storage Instruction-20°C
- UNSPSC12352200