Macbecin

MedChem Express

Macbecin [73341-72-7]

10

73341-72-7

Research Use Only

C30H42N2O8

558.66

Macbecin is a stable HSP90 inhibitor by binding to the ATP-binding site with an IC 50 of 2 microM and a K d of 0.24 microM. Macbecin exhibits antitumor and cytocidal activities [1] .

O=C(C(NC(/C(C)=C/C=C/[C@H](C)[C@@H](OC(N)=O)/C(C)=C/[C@H](C)[C@H](OC)[C@@H](OC)C[C@@H]1C)=O)=C2)C([C@]1([H])OC)=CC2=O

12352200