MAFA Polyclonal Antibody

Reddot Biotech

MAFA Polyclonal Antibody

5

Western Blot, ELISA

Research Use Only

Polyclonal

1.2 mg/ml

Unconjugated

MAFA

MAF bZIP transcription factor A

hMafA; INSDM; pancreatic beta-cell-specific transcriptional activator; RIPE3b1; RIPE3b1 factor; transcription factor MafA; transcription factor RIPE3b1; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A

Rabbit

IgG

Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members.MAFA acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity.

Human, Mouse

-20°C

12352203