MAFG antibody
GTX114541
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMAFG
Overview
- SupplierGeneTex
- Product NameMAFG antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.53 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID4097
- Target nameMAFG
- Target descriptionMAF bZIP transcription factor G
- Target synonymsbasic leucine zipper transcription factor MafG; hMAF; transcription factor MafG; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
- HostRabbit
- IsotypeIgG
- Protein IDO15525
- Protein NameTranscription factor MafG
- Scientific DescriptionGlobin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).[supplied by OMIM]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- MAFG-driven astrocytes promote CNS inflammation. Wheeler MA et al., 2020 Feb, NatureRead more
- A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism. Pradas-Juni M et al., 2020 Jan 31, Nat CommunRead more
- miR-128 Is Implicated in Stress Responses by Targeting MAFG in Skeletal Muscle Cells. Caggiano R et al., 2017, Oxid Med Cell LongevRead more
- MAFG is a transcriptional repressor of bile acid synthesis and metabolism. de Aguiar Vallim TQ et al., 2015 Feb 3, Cell MetabRead more