MAGEA3 Antibody, HRP conjugated

Cusabio

MAGEA3 Antibody, HRP conjugated

20

ELISA

Research Use Only

Polyclonal

HRP

MAGEA3

MAGE family member A3

antigen MZ2-D; cancer/testis antigen 1.3; cancer/testis antigen family 1, member 3; CT1.3; HIP8; HYPD; MAGE3; MAGE-3 antigen; MAGEA6; melanoma antigen family A, 3; melanoma antigen family A3; melanoma-associated antigen 3

Rabbit

IgG

Melanoma-associated antigen 3

Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Human

-20°C or -80°C

12352203