MAGLi 432

MedChem Express

MAGLi 432

10

Research Use Only

C22H24BrClN2O2

463.80

MAGLi 432 is a non-covalent, potent, highly selective, and reversible MAGL inhibitor. MAGLi 432 binds with high affinity to the MAGL active site, with IC 50 values of 4.2 nM (human enzyme) and 3.1 nM (mouse enzyme). MAGLi 432 can be used in the research of chronic inflammation, blood-brain barrier dysfunction, neurological disorders such as multiple sclerosis, Alzheimers disease and Parkinsons disease [1] .

O=C(C1=CC=CC(OC)=C1Br)N2C[C@](CC[C@H](C3=CC=C(Cl)C=C3)C4)([H])N4CC2

12352200