Mal-PEG4-VC-PAB-DMEA-PNU-159682 [2259318-52-8]

TargetMol Chemicals

Mal-PEG4-VC-PAB-DMEA-PNU-159682 [2259318-52-8]

16

2259318-52-8

Chemical

Research Use Only

Mal-PEG4-VC-PAB-DMEA-PNU-159682

C74H98N10O27

1559.62

Mal-PEG4-VC-PAB-DMEA-PNU-159682 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) therapy. It combines the ADC linker, Mal-PEG4-VC-PAB, with the potent ADC cytotoxin, DMEA-PNU-159682. The cytotoxin, DMEA-PNU-159682, is derived from metabolites of nemorubicin (MMDX) found in liver microsomes, as well as the ADC cytotoxin PNU-159682 [1].

3 years

O([C@@H]1C2=C(C(O)=C3C(=C2O)C(=O)C=4C(C3=O)=CC=CC4OC)C[C@](C(COC(N(CCN(C(OCC5=CC=C(NC([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCNC(CCN6C(=O)C=CC6=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C5)=O)C)C)=O)=O)(O)C1)[C@H]7C[C@@]8(N9[C@](O[C@@]8([C@H](C)O7)[H])([C@@H](OC)OCC9)[H])[H]

-20°C

12352200