Malformin C [59926-78-2]

Name: Malformin C [59926-78-2]
SKU: AG-CN2-0107_A27
Availability: BackOrder

AG-CN2-0107

CAS Number59926-78-2

Product group Chemicals

Estimated Purity>95%

Molecular Weight529.7

Overview

Supplier
AdipoGen Life Sciences
Product Name
Malformin C [59926-78-2]
Delivery Days Customer
10
CAS Number
59926-78-2
Certification
Research Use Only
Estimated Purity
>95%
Hazard Information
Warning
Molecular Formula
C23H39N5O5S2
Molecular Weight
529.7
Scientific Description
Chemical. CAS: 59926-78-2. Formula: C23H39N5O5S2. MW: 529.7. Synthetic. Originally isolated from Aspergillus niger FKI-2342. Peptide antibiotic. Induces root curvature and malformation in plants. Antibacterial, antimalarial and antitrypanosomal. Disrupts the cell cycle at the G2 checkpoint of cancer cells, leading to sensitization of the cancer cells to anti-cancer reagents. - Peptide antibiotic [1]. Induces root curvature and malformation in plants [1]. Antibacterial [1, 2], antimalarial and antitrypanosomal [4]. Disrupts the cell cycle at the G2 checkpoint of cancer cells, leading to sensitization of the cancer cells to anti-cancer reagents [3].
SMILES
CC(C)C[C@@H]1NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H]2CSSC[C@@H](NC1=O)C(=O)N2)C(C)C
Storage Instruction
2°C to 8°C,-20°C
UNSPSC
12352200

Malformin C, a new metabolite of Aspergillus niger: R.J. Anderegg, et al.; JACS 98, 3365 (1976)
Production and antibacterial activity of malforming C, a toxic metabolite of Aspergillus niger: B. Kobbe, et al.; Appl. Environ. Microbiol. 33, 996 (1977)
Fungal malformins inhibit bleomycin-induced G2 checkpoint in Jurkat cells: K. Hagimori, et al.; Biol. Pharm. Bull. 30, 1379 (2007)
Solid-phase synthesis and biological activity of malformin C and its derivatives: Y. Kojima, et al.; J. Antibiot. (Tokyo) 62, 681 (2009)