ICC/IF analysis of HeLa cells using GTX03413 MAN1B1 antibody [3C2]. Green : Primary antibody Red : alpha tubulin Blue : DAPI
![IHC-P analysis of human breast cancer using GTX03413 MAN1B1 antibody [3C2].](https://www.genetex.com/upload/website/prouct_img/normal/GTX03413/GTX03413_20220210_IHC-P_w_23053123_796.webp "IHC-P analysis of human breast cancer using GTX03413 MAN1B1 antibody [3C2].")
![WB analysis of various sample lysates using GTX03413 MAN1B1 antibody [3C2]. Lane 1 : NTERA-2 whole cell lysate Lane 2 : A431 whole cell lysate](https://www.genetex.com/upload/website/prouct_img/normal/GTX03413/GTX03413_20220210_WB_w_23053123_935.webp "WB analysis of various sample lysates using GTX03413 MAN1B1 antibody [3C2]. Lane 1 : NTERA-2 whole cell lysate Lane 2 : A431 whole cell lysate")
ICC/IF analysis of HeLa cells using GTX03413 MAN1B1 antibody [3C2]. Green : Primary antibody Red : alpha tubulin Blue : DAPI
MAN1B1 antibody [3C2]
GTX03413
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMAN1B1
Overview
- SupplierGeneTex
- Product NameMAN1B1 antibody [3C2]
- Delivery Days Customer9
- Antibody SpecificityWe do not recommend use of this product for Mouse.,Knockdown/Knockout validation was supported by references (PMID: 26205822).
- Application Supplier NoteWB: 1:500-1:1000. ICC/IF: 1:100. IHC-P: 1:200. IP: 1:10-1:100. ELISA: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3C2
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID11253
- Target nameMAN1B1
- Target descriptionmannosidase alpha class 1B member 1
- Target synonymsendoplasmic Reticulum Class I alpha-mannosidase; endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase; endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1; ER alpha 1,2-mannosidase; ERMAN1; ERManI; Man9GlcNAc2-specific processing alpha-mannosidase; MANA-ER; MRT15
- HostMouse
- IsotypeIgG1
- Protein IDQ9UKM7
- Protein NameEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
- Scientific DescriptionThis gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- ERManI (Endoplasmic Reticulum Class I alpha-Mannosidase) Is Required for HIV-1 Envelope Glycoprotein Degradation via Endoplasmic Reticulum-associated Protein Degradation Pathway. Zhou T et al., 2015 Sep 4, J Biol ChemRead more