WB analysis of various sample lysates using GTX03414 MAN1B1 antibody. Dilution : 1:3000 Loading : 25 microg per lane
WB analysis of various sample lysates using GTX03414 MAN1B1 antibody. Dilution : 1:3000 Loading : 25 microg per lane
MAN1B1 antibody
GTX03414
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMAN1B1
Overview
- SupplierGeneTex
- Product NameMAN1B1 antibody
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID11253
- Target nameMAN1B1
- Target descriptionmannosidase alpha class 1B member 1
- Target synonymsendoplasmic Reticulum Class I alpha-mannosidase; endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase; endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1; ER alpha 1,2-mannosidase; ERMAN1; ERManI; Man9GlcNAc2-specific processing alpha-mannosidase; MANA-ER; MRT15
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203