MAP3K5-IN-1 [2226941-29-1]

TargetMol Chemicals

MAP3K5-IN-1 [2226941-29-1]

16

Research Use Only

C28H24N4O4

480.51

Compound 7, also known as 3-O-Demethyl-4-N-demethyl-4-N-acetyl-4-epi-staurosporine, serves as an inhibitor of protein kinases, displaying IC50 values of 0.092 microM for PKC-alpha, 0.26 microM for ROCK, and 0.77 microM for ASK1. Additionally, this compound exhibits significant cytotoxicity towards PC-3 cancer cells, with an IC50 of 0.16 microM [1].

C[C@]12N3C=4C5=C(C6=C(C4C=7C3=CC=CC7)CNC6=O)C=8C(N5[C@](O1)(C[C@H](NC(C)=O)[C@H]2O)[H])=CC=CC8

-20°C

51202000