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Marco antibody [PLK-1]

Research Use Only
GTX54470
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
Product group Antibodies
ReactivityBovine, Human
TargetMARCO
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    Marco antibody [PLK-1]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody stains alveolar macrophages by recognizing the extracellular domain of MARCO. The monoclonal antibody PLK-1 binds specifically to MARCO, and has been shown to partially block ligand binding.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    PLK-1
  • Concentration
    100 ug/ml
  • Conjugate
    Unconjugated
  • Gene ID8685
  • Target name
    MARCO
  • Target description
    macrophage receptor with collagenous structure
  • Target synonyms
    macrophage receptor MARCO; SCARA2; scavenger receptor class A, member 2; SR-A6
  • Host
    Mouse
  • Isotype
    IgG3
  • Scientific Description
    The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008]
  • Reactivity
    Bovine, Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203