Marco antibody [PLK-1]

GeneTex

Marco antibody [PLK-1]

9

This antibody stains alveolar macrophages by recognizing the extracellular domain of MARCO. The monoclonal antibody PLK-1 binds specifically to MARCO, and has been shown to partially block ligand binding.

ICC/IF: 0.6 microg/ml. IHC-Fr: 5microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking

Research Use Only

Monoclonal

PLK-1

100 ug/ml

Unconjugated

Liquid

MARCO

macrophage receptor with collagenous structure

macrophage receptor MARCO; SCARA2; scavenger receptor class A, member 2; SR-A6

Mouse

IgG3

Macrophage receptor MARCO

The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008]

Bovine, Human

2°C to 8°C

12352203