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Margatoxin

Research Use Only
PAR-4290-s
Biosynth
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    Biosynth
  • Product Name
    Margatoxin
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Scientific Description
    (Scorpion, Centruroides margaritatus) Thr-Ile-Ile-Asn-Val-Lys-Cys-Thr-Ser-Pro-Lys-Gln-Cys-Leu-Pro-Pro-Cys-Lys-Ala-Gln-Phe-Gly-Gln-Ser-Ala-Gly-Ala-Lys-Cys-Met-Asn-Gly-Lys-Cys-Lys-Cys-Tyr-Pro-His (Disulfide bonds between Cys7-Cys29,Cys13-Cys34, and Cys17-Cys36) (M.W. 4178.9) C178H286N52O50S7 [145808-47-5] Volgate-Dependent K+ Channel Blocker (Specific for Kv1.3 Channel) R.J. Leonard, M.L. Garcia, R.S. Slaughter, and J.P. Reuben, Proc. Natl. Acad. Sci. U.S.A., 89, 10094 (1992). (Pharmacol.) M. Garcia-Calvo, R.J. Leonard, J. Novick, S.P. Stevens, W. Schmalhofer, G.J. Kaczorowski, and M.L. Garcia, J. Biol. Chem., 268, 18866 (1993). (Original) M.A. Bednarek, R.M. Bugianesti, R.J. Leonard, and J.P. Felix, Biochem. Biophys. Res. Commun., 198, 619 (1994). (Chem. Synthesis & S-S Bond) H.G. Knaus, R.O.A. Koch, A. Eberhart, G.J. Kaczorowski, M.L. Garcia, and R.S. Slaughter, Biochemistry, 34,13627 (1995). (Pharmacol.)
  • Source
    (Scorpion, Centruroides margar
  • UNSPSC
    12352202