MASM7

MedChem Express

MASM7

5

Research Use Only

99.85

C22H23N5O2S2

453.58

MASM7 is a mitofusin activator, and can achieve mitochondrial fusion via mitofusins. MASM7 can increase Mito AR with an EC 50 value of 75 nM in MEFs in concentration-responsively, and can promote mitochondrial fusion by directly activating MFN2 or MFN. MASM7 also demonstrates direct binding to the HR2 domain of MFN2 with K d value of 1.1 microM [1] .

O=C(N)C1=C(SC2=C1CCC2)NC(C(C)SC3=NN=C(C4CC4)N3C5=CC=CC=C5)=O

-20°C,2°C to 8°C

12352200