MAZ51
S0765
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameMAZ51
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionMAZ51 is a potent and selective inhibitor of vascular endothelial growth factor receptor (VEGFR)-3 (Flt-4) tyrosine kinase. MAZ51 induces cell rounding and G2/M cell cycle arrest in glioma cells through phosphorylation of Akt/GSK3bèta and activation of RhoA. MAZ51 inhibits the proliferation and induces the apoptosis of a variety of non-VEGFR-3-expressing tumor cell lines.
- UNSPSC12352200
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