MBM-17

MedChem Express

MBM-17 [2083621-90-1]

10

2083621-90-1

C28H28N6O2

480.56

MBM-17 is a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC 50 of 3 nM. It effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis . MBM-55 shows antitumor activities, and no obvious toxicity to mice [1] .

NC(C(C=C1)=C(OCC2=CC=CC=C2)C=C1C3=CN=C4N3C=CC(C5=CN(CCN(C)C)N=C5)=C4)=O

-20°C,2°C to 8°C

12352200