MBTPS1 Antibody, Biotin conjugated

Cusabio

MBTPS1 Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

MBTPS1

membrane bound transcription factor peptidase, site 1

endopeptidase S1P; membrane-bound transcription factor site-1 protease; PCSK8; proprotein convertase subtilisin/kexin type 8; S1P; SEDKF; site-1 protease; SKI-1; subtilisin/kexin isozyme-1

Rabbit

IgG

Membrane-bound transcription factor site-1 protease

Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.

Human

-20°C or -80°C

12352203