MBTPS2 antibody

GeneTex

MBTPS2 antibody

9

ICC/IF: 1:100~1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoCytoChemistry

Research Use Only

Polyclonal

Unconjugated

MBTPS2

membrane bound transcription factor peptidase, site 2

BRESEK; endopeptidase S2P; IFAP; keratosis follicularis spinulosa decalvans; KFSD; KFSDX; membrane-bound transcription factor protease, site 2; membrane-bound transcription factor site-2 protease; OI19; OLMSX; S2P; site-2 protease; SREBPs intramembrane protease; sterol regulatory element-binding proteins intramembrane protease

Rabbit

IgG

Membrane-bound transcription factor site-2 protease

This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009]

-20°C or -80°C,2°C to 8°C

12352203