MC-Gly-Gly-Phe-Gly-GABA-Exatecan [1599439-52-7]

TargetMol Chemicals

MC-Gly-Gly-Phe-Gly-GABA-Exatecan [1599439-52-7]

16

Research Use Only

C53H58FN9O12

1032.08

MC-Gly-Gly-Phe-Gly-GABA-Exatecan, functioning both as an ADC linker agent and a topoisomerase inhibitor (Exatecan), displays cytotoxic and antitumor properties in vitro and in vivo [1] [2]. It specifically targets various antibodies and boasts an IC 50 of 22 microM.

N(C(CCCNC(CNC([C@H](CC1=CC=CC=C1)NC(CNC(CNC(CCCCCN2C(=O)C=CC2=O)=O)=O)=O)=O)=O)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8

-20°C

12352200