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ProductsBack/Mcl1-IN-12 [2042211-12-9]
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Mcl1-IN-12 [2042211-12-9]

Research Use Only
T11974
TargetMol Chemicals
CAS Number2042211-12-9
DownloadMSDS
Product group Chemicals
Molecular Weight803
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Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Mcl1-IN-12 [2042211-12-9]
  • Delivery Days Customer
    16
  • CAS Number
    2042211-12-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Mcl1-IN-12
  • Molecular Formula
    C45H46N4O6S2
  • Molecular Weight
    803
  • Scientific Description
    Mcl1-IN-12 has anti-tumor activity.It is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 microM, respectively.
  • Shelf life instruction
    3 years
  • SMILES
    O=C(NC1=CC=C(C=C1)C(=O)NS(=O)(=O)C2=CC=C(NCCSC=3C=CC=CC3)C(=C2)N(=O)=O)C4=CC=C(C=C4)C(=C)C=5C=C6C(=CC5C)C(C)(C)CCC6(C)C
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

References

  • Wang M, et al. Design, synthesis, and activity evaluation of selective inhibitors of anti-apoptotic Bcl-2 proteins: The effects on the selectivity of the P1 pockets in the active sites. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5207-5211.
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