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CgoaEWY7O4qEXGWPAAAAABL_9u0264.png
Mcl1-IN-8
T16030
CAS Number678158-55-9
Product group Chemicals
Molecular Weight393.5
Overview
- SupplierTargetMol Chemicals
- Product NameMcl1-IN-8
- Delivery Days Customer14
- CAS Number678158-55-9
- Category SupplierChemical
- Chemical NameMcl1-IN-8
- Molecular FormulaC22H23N3O2S
- Molecular Weight393.5
- Scientific DescriptionMcl1-IN-8 is an Mcl-1-PUMA interface inhibitor (Ki: 0.3 uM). In cancer cells, Mcl1-IN-8 shows dual activity on reducing PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis.
- Shelf life instruction3 years
- SMILESC(=C1SC(=NC1=O)N2CCN(CCO)CC2)C3=CC=C(C=C3)C4=CC=CC=C4
- Storage Instruction-20°
- UNSPSC12352200
References
- Liu J, et al. Targeting the apoptotic Mcl-1-PUMA interface with a dual-acting compound. Oncotarget. 2017 Apr 20;8(33):54236-54242.Read more