MCM4 Antibody, FITC conjugated

Cusabio

MCM4 Antibody, FITC conjugated

20

Research Use Only

Polyclonal

FITC

MCM4

minichromosome maintenance complex component 4

CDC21; CDC54; DNA replication licensing factor MCM4; hCdc21; homolog of S. pombe cell devision cycle 21; IMD54; minichromosome maintenance deficient 4; NKCD; NKGCD; P1-CDC21

Rabbit

IgG

DNA replication licensing factor MCM4

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for \once per cell cycle\ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.

Human

-20°C or -80°C

12352203