MCT8 antibody

GeneTex

MCT8 antibody

9

WB: 1:300-1000. IHC-P: 1:50-400. FACS: 1:20-100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

SLC16A2

solute carrier family 16 member 2

AHDS; DXS128; DXS128E; MCT 7; MCT 8; MCT7; MCT8; monocarboxylate transporter 7; monocarboxylate transporter 8; MRX22; solute carrier family 16, member 2 (thyroid hormone transporter); X-linked PEST-containing transporter; XPCT

Rabbit

IgG

Monocarboxylate transporter 8

This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome. [provided by RefSeq, Mar 2012]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203