MCTS1 Polyclonal Antibody
RD268011A
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMCTS1
Overview
- SupplierReddot Biotech
- Product NameMCTS1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID28985
- Target nameMCTS1
- Target descriptionMCTS1 re-initiation and release factor
- Target synonymsmalignant T-cell amplified sequence 1; malignant T-cell-amplified sequence 1; MCT1; MCT-1; multiple copies in T-cell lymphoma-1; multiple copies T-cell malignancies
- HostRabbit
- IsotypeIgG
- Scientific DescriptionMCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203