Bio-Connect

MCUF-651

HY-149453
MedChem Express
Estimated Purity99.85
Product group Chemicals
Molecular Weight368.44
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MCUF-651
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Estimated Purity
    99.85
  • Molecular Formula
    C17H22F2N4OS
  • Molecular Weight
    368.44
  • Scientific Description
    MCUF-651 is an orally active guanylyl cyclase A receptor (GC-A) positive allosteric modulator (PAM) (KD: 397 nM ). MCUF-651 binds to GC-A and selectively enhances the binding of atrial natriuretic peptide (ANP) to GC-A. MCUF-651 enhances ANP-mediated cGMP generation in human cardiac, renal, and fat cells. MCUF-651 inhibits cardiomyocyte hypertrophy[1].
  • SMILES
    O=C(C1CN(CCC1)CCN(C)C)NC2=NC3=C(S2)C=C(F)C=C3F
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200