MCUF-651
HY-149453
Overview
- SupplierMedChem Express
- Product NameMCUF-651
- Delivery Days Customer5
- CertificationResearch Use Only
- Estimated Purity99.85
- Molecular FormulaC17H22F2N4OS
- Molecular Weight368.44
- Scientific DescriptionMCUF-651 is an orally active guanylyl cyclase A receptor (GC-A) positive allosteric modulator (PAM) (KD: 397 nM ). MCUF-651 binds to GC-A and selectively enhances the binding of atrial natriuretic peptide (ANP) to GC-A. MCUF-651 enhances ANP-mediated cGMP generation in human cardiac, renal, and fat cells. MCUF-651 inhibits cardiomyocyte hypertrophy[1].
- SMILESO=C(C1CN(CCC1)CCN(C)C)NC2=NC3=C(S2)C=C(F)C=C3F
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200