Immunohistochemistry of paraffin-embedded Human brain tissue using MDC1 Polyclonal Antibody at dilution 1:80
Immunohistochemistry of paraffin-embedded Human brain tissue using MDC1 Polyclonal Antibody at dilution 1:80
MDC1 Polyclonal Antibody
E-AB-12802
Product group Antibodies
Overview
- SupplierElabscience
- Product NameMDC1 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration1.2mg/ml
- Scientific DescriptionThe protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
- UNSPSC12352203