MDM2/4-p53-IN-1

MedChem Express

MDM2/4-p53-IN-1

10

Research Use Only

C32H22Cl2N6O3

609.46

MDM2/4-p53-IN-1 is a potent MDM2-p53 and MDM4-p53 inhibitor with IC50 values of 35.9, 57.4 nM, respectively. MDM2/4-p53-IN-1 shows antiproliferative activity.

O=C1NC2=CC(Cl)=CC=C2[C@@]13N(C4=CC=C(Cl)C=C4)N=C([C@@H]3C5=CC(O)=CC=C5)C(NC6=CC(N7N=CC=C7)=CC=C6)=O.[Relative stereochemistry]

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12352200