![MDM2(SMP14), CF640R conjugate, 0.1mg/mL [26628-22-8] MDM2(SMP14), CF640R conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2021/02/view_image-157.jpeg)
MDM2(SMP14), CF640R conjugate, 0.1mg/mL [26628-22-8]
BNC401721
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse, Rat
TargetMDM2
Overview
- SupplierBiotium
- Product NameMDM2(SMP14), CF640R conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSMP14
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID4193
- Target nameMDM2
- Target descriptionMDM2 proto-oncogene
- Target synonymsACTFS; double minute 2, human homolog of; p53-binding protein; E3 ubiquitin-protein ligase Mdm2; hdm2; HDMX; LSKB; MDM2 oncogene, E3 ubiquitin protein ligase; MDM2 proto-oncogene, E3 ubiquitin protein ligase; Mdm2, p53 E3 ubiquitin protein ligase homolog; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein; oncoprotein Mdm2
- HostMouse
- IsotypeIgG1
- Protein IDQ00987
- Protein NameE3 ubiquitin-protein ligase Mdm2
- Scientific DescriptionMDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203