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ProductsBack/Me7BIO [916440-98-7]
Chemical Structure
Chemical Structure
Chemical Structure

Me7BIO [916440-98-7]

Research Use Only
AG-MR-C0022
AdipoGen Life Sciences
CAS Number916440-98-7
DownloadMSDS
Product group Chemicals
Estimated Purity>95%
Molecular Weight370.2
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Me7BIO [916440-98-7]
  • Delivery Days Customer
    10
  • CAS Number
    916440-98-7
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Warning
  • Molecular Formula
    C17H12BrN3O2
  • Molecular Weight
    370.2
  • Scientific Description
    Chemical. CAS: 916440-98-7. Formula: C17H12BrN3O2. MW: 370.2. N-methylated inactive control compound for 7BIO (Prod. No. MR-C0020). Aryl hydrocarbon receptor (AhR) agonist; causes redistribution of AhR to the nucleus. - N-methylated inactive control compound for 7BIO (Prod. No. MR-C0020). Aryl hydrocarbon receptor (AhR) agonist; causes redistribution of AhR to the nucleus.
  • SMILES
    CN1C(=O)\C(=C2/NC3=CC=CC=C3/C/2=N\O)C2=C1C(Br)=CC=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    51202000

References

  • Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the anti-proliferative effects of indirubins: M. Knockaert, et al.; Oncogene 23, 4400 (2004)
  • Indirubin, the red shade of indigo: L. Meijer, et al. (Editors): In «Life in Progress», Station Biologique, Roscoff, 297 pp. (2006)
  • 7-Bromoindirubin-3'-oxime induces caspase-independent cell death: J. Ribas, et al.; Oncogene 25, 6304 (2006)
  • An integrated computational approach to the phenomenon of potent and selective inhibition of aurora kinases B and C by a series of 7-substituted indirubins: V. Myrianthopoulos, et al.; J. Med. Chem. 50, 4027 (2007)
  • Cutting edge: Necrosis activates the NLRP3 inflammasome: H. Li, et al.; J. Immunol. 183, 1528 (2009)