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IHC-P analysis of mouse brain tissue using GTX22828 MECP2 antibody. Right : Primary antibody Left : Negative control without primary antibody Antigen retrieval : 10mM sodium citrate (pH 6.0), microwaved for 8-15 min Dilution : 1:500
IHC-P analysis of mouse brain tissue using GTX22828 MECP2 antibody. Right : Primary antibody Left : Negative control without primary antibody Antigen retrieval : 10mM sodium citrate (pH 6.0), microwaved for 8-15 min Dilution : 1:500
IHC-P analysis of mouse brain tissue using GTX22828 MECP2 antibody. Right : Primary antibody Left : Negative control without primary antibody Antigen retrieval : 10mM sodium citrate (pH 6.0), microwaved for 8-15 min Dilution : 1:500

MECP2 antibody

GTX22828
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityDrosophila, Human, Mouse, Primate, Rat
TargetMecp2
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Overview

  • Supplier
    GeneTex
  • Product Name
    MECP2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1500. ICC/IF: 1:100-1:200. IHC-P: 1:200-1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID17257
  • Target name
    Mecp2
  • Target description
    methyl CpG binding protein 2
  • Target synonyms
    1500041B07Rik; D630021H01Rik; Mbd5; meCp-2 protein; methyl-CpG-binding protein 2; WBP1; WBP10
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9Z2D6
  • Protein Name
    Methyl-CpG-binding protein 2
  • Scientific Description
    DNA methyltransferases methylate the 5-position of cytosine in the context of CpG dinucleotides. DNA methylation is crucial for normal embryonic development, imprinting, and X-chromosome inactivation. Methyl CpG binding proteins (MeCPs) specifically recognize methylated regions of DNA and repress transcription both directly and by association with known corepressor proteins which include members of the Sin3 and histone deactylase protein families.
  • Reactivity
    Drosophila, Human, Mouse, Primate, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Association of CaMK2A and MeCP2 signaling pathways with cognitive ability in adolescents. Lee LC et al., 2021 Oct 4, Mol Brain
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  • Cocaine-mediated activation of microglia and microglial MeCP2 and BDNF production. Cotto B et al., 2018 Sep, Neurobiol Dis
    Read more