MED23 antibody

GeneTex

MED23 antibody

9

ICC/IF: 1:100~1:500. IHC-P: 1:50~1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

MED23

mediator complex subunit 23

130 kDa transcriptional co-activator; 133 kDa transcriptional co-activator; activator-recruited cofactor 130 kDa component; ARC130; cofactor required for Sp1 transcriptional activation subunit 3; CRSP130; CRSP133; CRSP3; DRIP130; mediator of RNA polymerase II transcription subunit 23; mental retardation, non-syndromic, autosomal recessive, 18; MRT18; SUR2; SUR-2; vitamin D3 receptor interacting protein

Rabbit

IgG

Mediator of RNA polymerase II transcription subunit 23

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012]

-20°C or -80°C,2°C to 8°C

12352203