Western blot analysis of extracts from Jurkat/K562 cells, using MED8 antibody.
Western blot analysis of extracts from Jurkat/K562 cells, using MED8 antibody.
MED8 Antibody
CSB-PA991036
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMED8
Overview
- SupplierCusabio
- Product NameMED8 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID112950
- Target nameMED8
- Target descriptionmediator complex subunit 8
- Target synonymsactivator-recruited cofactor 32 kDa component; ARC32; mediator of RNA polymerase II transcription subunit 8; mediator of RNA polymerase II transcription subunit MED8
- HostRabbit
- IsotypeIgG
- Protein IDQ96G25
- Protein NameMediator of RNA polymerase II transcription subunit 8
- Scientific DescriptionComponent of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins. Brower C.S., Proc. Natl. Acad. Sci. U.S.A. 99:10353-10358(2002). Gregory S.G., Nature 441:315-321(2006). Naeaer A.M., Nature 398:828-832(1999).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203