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ProductsBack/MEGA-8 (ultrapure) [85316-98-9]
Chemical Structure
Chemical Structure
Chemical Structure

MEGA-8 (ultrapure) [85316-98-9]

Research Use Only
AG-CC1-0007
AdipoGen Life Sciences
Estimated Purity>99%
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Product group Chemicals
Molecular Weight321.4
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    MEGA-8 (ultrapure) [85316-98-9]
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    >99%
  • Hazard Information
    Non-hazardous
  • Molecular Formula
    C15H31NO6
  • Molecular Weight
    321.4
  • Scientific Description
    Chemical. CAS: 85316-98-9. Formula: C15H31NO6. MW: 321.4. Non-ionic water-soluble detergent with nondenaturing properties. Transparent in the UV region. Relatively high critical micelle concentration (CMC) value (79mM/l). Ideal for studying the conformation and function of proteins, keeping the secondary and tertiary structure intact, therefore suited for solubilizing membrane proteins without altering biological activity. Efficiently separates hydrophilic proteins from membrane spanning, hydrophobic proteins. Ideal for use as membrane protein solubilizer. - Non-ionic water-soluble detergent with nondenaturing properties. Transparent in the UV region. Relatively high critical micelle concentration (CMC) value (79mM/l). Ideal for studying the conformation and function of proteins, keeping the secondary and tertiary structure intact, therefore suited for solubilizing membrane proteins without altering biological activity. Efficiently separates hydrophilic proteins from membrane spanning, hydrophobic proteins. Ideal for use as membrane protein solubilizer.
  • SMILES
    CCCCCCCC(=O)N(C)CC(O)C(O)C(O)C(O)CO
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • The structures of 1-deoxy-(N-methyloctanamido)-D-glucitol (MEGA-8) and 1-deoxy-(N-methylundecanamido)-D-glucitol (MEGA-11): G.A. Jeffrey & H. Maluszynska; Acta Crystallogr. B 45, 447 (1989)
  • Solubility properties of the alkylmethylglucamide surfactants: A. Walter, et al.; Biochim. Biophys. Acta 1029, 67 (1990)
  • Differential solubilization of lipids along with membrane proteins by different classes of detergents: P. Banerjee, et al.; Chem. Phys. Lipids 77, 65 (1995)
  • Salt Effect on Critical Micelle Concentrations of Nonionic Surfactants, N-Acyl-N-methylglucamides (MEGA-n): S. Miyagishi, et al.; J. Colloid Interface Sci. 238, 91 (2001)
  • Blending effects on adsorption and micellization of different membrane protein solubilizers: a thermodynamic study on three mixed systems of CHAPS with MEGA-8, -9 and -10 in pH 7.2 phosphate buffer solution: J.S. Ko, et al.; Colloids Surf. B Biointerfaces 45, 90 (2005)