Chemical Structure
Melanin Production Inhibitor A3B5 [346721-60-6]
AG-CR1-3605
Overview
- SupplierAdipoGen Life Sciences
- Product NameMelanin Production Inhibitor A3B5 [346721-60-6]
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity>98% (NMR)
- Hazard InformationNon-hazardous,Warning
- Molecular FormulaC16H17NO2
- Molecular Weight255.3
- Scientific DescriptionChemical. CAS: 346721-60-6. Formula: C16H17NO2. MW: 255.3. Non-cytotoxic melanogenesis inhibitor. Potential depigmentation agent. Tyrosinase-related protein 2 (TRP-2) expression inhibitor, via proteasomal degradation. Inhibits the proliferation of melanocytes and melanoma cells through cell cycle arrest in G1. Moderate skin tumor growth suppressor in vivo. - Non-cytotoxic melanogenesis inhibitor. Potential depigmentation agent. Tyrosinase-related protein 2 (TRP-2) expression inhibitor, via proteasomal degradation. Inhibits the proliferation of melanocytes and melanoma cells through cell cycle arrest in G1. Moderate skin tumor growth suppressor in vivo.
- SMILESCOC1=CC(=CC=C1)C(=O)NC1=CC(C)=CC(C)=C1
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352200
References
- Identification of a potent and noncytotoxic inhibitor of melanin production: S. Hwang, et al.; Bioorg. Med. Chem. 18, 5602 (2010)
- N-(3,5-dimethylphenyl)-3-methoxybenzamide (A(3)B(5)) targets TRP-2 and inhibits melanogenesis and melanoma growth: E.J. Lee, et al.; J. Invest. Dermatol. 131, 1701 (2011)