IHC-P analysis of human melanoma tissue using GTX20906 Melanoma antibody [HMB45] (ready-to-use).
IHC-P analysis of human melanoma tissue using GTX20906 Melanoma antibody [HMB45] (ready-to-use).
Melanoma antibody [HMB45] (ready-to-use)
GTX20906
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
Overview
- SupplierGeneTex
- Product NameMelanoma antibody [HMB45] (ready-to-use)
- Delivery Days Customer9
- Antibody SpecificityThis antibody reacts with a neuraminidase sensitive oligosaccharide side chain of a glycoconjugate present in immature melanosomes. It reacts with junctional and blue nevus cells. Non-melanocytic cells are negative.
- Application Supplier Note*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHMB45
- ConjugateUnconjugated
- HostMouse
- IsotypeIgG1
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Loss of GPNMB Causes Autosomal-Recessive Amyloidosis Cutis Dyschromica in Humans. Yang CF et al., 2018 Feb 1, Am J Hum GenetRead more
- Interferon-inducible T-cell alpha chemoattractant (ITAC) induces the melanocytic migration and hypopigmentation through destabilizing p53 via histone deacetylase 5: a possible role of ITAC in pigment-related disorders. Lee E et al., 2017 Jan, Br J DermatolRead more
- Hyperosmotic stress reduces melanin production by altering melanosome formation. Bin BH et al., 2014, PLoS OneRead more