MELK-8a
HY-100368
CAS Number1922153-17-0
Product group Chemicals
Estimated Purity98.32
Molecular Weight432.56
Overview
- SupplierMedChem Express
- Product NameMELK-8a [1922153-17-0]
- Delivery Days Customer10
- CAS Number1922153-17-0
- CertificationResearch Use Only
- Estimated Purity98.32
- Molecular FormulaC25H32N6O
- Molecular Weight432.56
- Scientific DescriptionMELK-8a (NVS-MELK8a) is a highly potent and selective maternal embryonic leucine zipper kinase ( MELK ) inhibitor with IC 50 of 2 nM. MELK-8a also inhibits Flt3 (ITD), Haspin, PDGFRalpha with IC 50 s of 0.18, 0.19, and 0.42 microM, respectively. MELK plays an essential role in regulating cell mitosis in a subset of cancer cells [1] .
- SMILESCN(CC1)CCN1C2=CC=C(N3C=C(C4=CC=NC=C4OCC5CCNCC5)C=N3)C=C2
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200