Western blot analysis of extracts from HuvEc cells, using MEN1 antibody.
Western blot analysis of extracts from HuvEc cells, using MEN1 antibody.
MEN1 Antibody
CSB-PA108807
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetMEN1
Overview
- SupplierCusabio
- Product NameMEN1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4221
- Target nameMEN1
- Target descriptionmenin 1
- Target synonymsMEAI; menin; SCG2
- HostRabbit
- IsotypeIgG
- Protein IDO00255
- Protein NameMenin
- Scientific DescriptionEssential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates Lys-4 of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression By similarity. May be involved in DNA repair. Chandrasekharappa S.C., Science 276:404-407(1997). Jin S., Cancer Res. 63:4204-4210(2003). Schnepp R.W., Cancer Res. 64:6791-6796(2004).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203