Menin-MLL inhibitor 34

MedChem Express

Menin-MLL inhibitor 34

9

Research Use Only

C40H54FN9O4S

775.98

Menin-MLL inhibitor 34 (Compound 37) is a selective and potent Menin-MLL inhibitor, with an IC50 of 18.21 nM for Menin. Menin-MLL inhibitor 34 has long-lasting anti-leukemic effects by reducing Menin protein levels and down-regulating MEN1 transcription[1].

O=C(N(CC)C(C)C)C1=CC(F)=CC=C1NC2=CN=CN=C2N3CCN(CC4CN(C5=CC=C(S(=O)(C6CN(C(/C=C/CN(C)C)=O)C6)=O)C=C5)C4)C(C)C3

12352200