Mer-NF5003F [149598-70-9]

MedChem Express

Mer-NF5003F [149598-70-9]

5

149598-70-9

Research Use Only

C23H30O5

386.48

Mer-NF5003F (Stachybotrydial; F 1839M), a sesquiterpene isolated from Stachybotrys, inhibits avian medulloblastoma virus (AMV) protease (IC50=7.8 microM). Mer-NF5003F inhibits sialyltransferase 6N (ST6N), ST3O, and ST3N (IC50=0.61, 6.7, and 10 microg/mL, respectively), and fucosyltransferase (IC50=11.3 microg/mL). Mer-NF5003F has in vitro activity against herpes simplex virus HSV-1 (IC50=4.32 microg/mL) and multidrug-resistant Plasmodium falciparum K1 strain (IC50=0.85 microg/mL).

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