Metallo-beta-lactamase-IN-16

MedChem Express

Metallo-beta-lactamase-IN-16

9

Research Use Only

C16H16N8O4S3

480.54

Metallo-beta-lactamase-IN-16 (compound 18) is a sulfone containing metallo-beta-lactamase inhibitor with an anti-bacterial activity. Metallo-beta-lactamase-IN-16 inhibits NDM-1 (New Dehli metallo-beta-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona integron-encoded metallo-beta-lactamase), and VIM-2 with IC50 values of 0.16 nM, 0.23 nM, 0.31 nM and 1.0 nM, respectively[1].

NCCS(=O)(C1=CC=C(C(C2=NNN=N2)=C1S(N)(=O)=O)C3=CC=CC4=C3N=C(S4)N)=O

12352200