Metergoline

MedChem Express

Metergoline [17692-51-2]

10

17692-51-2

Research Use Only

99.89

C25H29N3O2

403.52

Metergoline is a serotonin (5-HT) receptor and dopamine receptors antagonist, with pK i s of 8.64, 8.75 and 8.75 for 5-HT 2A , 5-HT 2B and 5-HT 2C , respectively. Metergoline is a high-affinity ligand for the h5-HT 7 receptor, with a K i of 16 nM. Metergoline is also a reversible neural Na + channels inhibitor. Metergoline is commonly used for the research of seasonal affective disorder, prolactin hormone regulation [1] [2] [3] .

O=C(OCC1=CC=CC=C1)NC[C@H](C[C@@]23[H])CN(C)[C@]2([H])CC4=CN(C)C5=CC=CC3=C54

-20°C

12352200