Methiothepin (maleate)

MedChem Express

Methiothepin (maleate) [19728-88-2]

10

19728-88-2

C24H28N2O4S2

472.62

Methiothepin maleate is a potent and non-selective 5-HT 2 receptor antagonist, with p K d s of 7.10 (5-HT 1A ), 7.28 (5HT 1B ), 7.56 (5HT 1C ), 6.99 (5HT 1D ), 7.0 (5-HT 5A ), 7.8 (5-HT 5B ), 8.74 (5-HT 6 ), and 8.99 (5-HT 7 ), and p K i s of 8.50 (5HT 2A ), 8.68 (5HT 2B ), and 8.35 (5HT 2C ).

CN1CCN(C2CC3=CC=CC=C3SC4=CC=C(SC)C=C24)CC1.OC(/C=C\C(O)=O)=O

12352200