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Methoxyamine (hydrochloride) (Standard)

HY-Y0958R
MedChem Express
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Methoxyamine (hydrochloride) (Standard)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Methoxyamine (hydrochloride) (Standard) is the analytical standard of Methoxyamine (hydrochloride). This product is intended for research and analytical applications. Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor. Methoxyamine hydrochloride binds to 3 hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents [1] [2] .
  • UNSPSC
    41116135