Methylspinazarin [41768-12-1]

TargetMol Chemicals

Methylspinazarin [41768-12-1]

999

Chemical

Research Use Only

Methylspinazarin

C11H8O6

236.179

Methylspinazarin is a naphthoquinone bacterial metabolite that has been found in Streptomyces and is an inhibitor of catechol O-methyltransferase (COMT; IC50 = 0.8 microg/ml).1 It is selective for COMT over tyrosine hydroxylase, DOPA decarboxylase, and dopamine-beta-hydroxylase at 100 microg/ml. Methylspinazarin decreases blood pressure in spontaneously hypertensive rats when administered at a dose of 50 mg/kg.

3 years

Cc1cc(O)c2C(=O)C(O)=C(O)C(=O)c2c1O - t:9 -

-20°C

12352200